Thymomectomy plus total thymectomy versus simple thymomectomy for early-stage thymoma without myasthenia gravis: a European Society of Thoracic Surgeons Thymic Working Group Study.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Guerrera Francesco, Falcoz Pierre Emmanuel, Moser Bernhard, van Raemdonck Dirk, Bille' Andrea, Toker Alper, Spaggiari Lorenzo, Ampollini Luca, Filippini Claudia, Thomas Pascal Alexandre, Verdonck Bram, Mendogni Paolo, Aigner Clemens, Voltolini Luca, Novoa Nuria, Patella Miriam, Mantovani Sara, Bravio Ivan Gomes, Zisis Charalambos, Guirao Angela, Londero Francesco, Congregado Miguel, Rocco Gaetano, Du Pont Bert, Martucci Nicola, Esch Matthias, Brunelli Alessandro, Detterbeck Frank C, Venuta Federico, Weder Walter, Ruffini Enrico, European Society of Thoracic Surgeons (ESTS) Thymic Working Group Participating Centers, Klepetko Walter, Olland Anne, Du Pont Bert, Nonaka Daisuke, Ozkan Berker, Lo Iacono Giorgio, Braggio Cesare, Filosso Pier Luigi, Brioude Geoffrey, van Schil Paul, Nosotti Mario, Valdivia Daniel, Bongiolatti Stefano, Inci Ilhan, Dimitra Rontogianni, Sànchez David, Grossi William, Moreno-Merino Sergio, Teschner Martin
Аннотация
METHODS: A total of 498 non-MG patients with pathological stage I thymoma were included in the study. TT was performed in 466 (93.6%) of 498 patients who had surgery with curative intent; ST was done in 32 (6.4%). The completeness of resection, the rate of complications, the 30-day mortality, the overall recurrence and the freedom from recurrence were compared. We performed crude and propensity score-adjusted comparisons by surgical approach (ST vs TT).
RESULTS: TT showed the same rate of postoperative complications, 30-day mortality and postoperative length of stay as ST. The 5-year overall survival rate was 89% in the TT group and 55% in the ST group. The 5-year freedom from recurrence was 96% in the TT group and 79% in the ST group.
CONCLUSION: Patients with early-stage thymoma without MG who have a TT show significantly better freedom from recurrence than those who have an ST, without an increase in postoperative morbidity rate.