Neutropenic enterocolitis and Clostridium septicum infection in patients with agranulocytosis.

Two patients with previously undiagnosed agranulocytosis had rapidly fatal Clostridium septicum sepsis and neutropenic enterocolitis. This toxigenic organism has a known predilection for cecal lesions. The association reported herein suggests that C septicum may be the cause of this necrotizing enteropathy.