Diagnostic cytopathology · 2025
FNAC Diagnosis of Rare Port-Site Metastasis in Gallbladder Cancer Post-Cholecystectomy.
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Gupta Arushi, Aden Durre, Khan Sabina, Ahmad Nehal
Аннотация
BACKGROUND: Port-site metastasis (PSM) following laparoscopic cholecystectomy (LC) for unsuspected gallbladder carcinoma (GBC) is a rare occurrence. Fine Needle Aspiration Cytology is a simple and time-saving technique, thus it has proven useful in diagnosing such metastases.
CASE REPORT: We present a case of a 45-year-old female who developed painful, multinodular epigastric swellings 2 years post-LC, initially performed for presumed benign cholelithiasis. FNAC of the port-site swelling revealed hypercellular smears with malignant epithelial cells, leading to a diagnosis of poorly differentiated malignancy. Follow-up imaging and histopathology confirmed incidental primary gallbladder carcinoma.
DISCUSSION: Port site metastasis in gallbladder carcinoma has a poor prognosis; thus, early detection and intervention are essential. Advanced imaging and FNAC under guidance serve as critical tools for early diagnosis, especially in cases lacking prior histological examination.
CONCLUSION: This case highlights the critical role of vigilant post-surgical monitoring and comprehensive histopathological analysis following cholecystectomy, especially in areas with a higher incidence of gallbladder carcinoma. FNAC also plays a valuable diagnostic modality for early detection and management of Port site metastasis in unsuspected gallbladder carcinoma cases.
CASE REPORT: We present a case of a 45-year-old female who developed painful, multinodular epigastric swellings 2 years post-LC, initially performed for presumed benign cholelithiasis. FNAC of the port-site swelling revealed hypercellular smears with malignant epithelial cells, leading to a diagnosis of poorly differentiated malignancy. Follow-up imaging and histopathology confirmed incidental primary gallbladder carcinoma.
DISCUSSION: Port site metastasis in gallbladder carcinoma has a poor prognosis; thus, early detection and intervention are essential. Advanced imaging and FNAC under guidance serve as critical tools for early diagnosis, especially in cases lacking prior histological examination.
CONCLUSION: This case highlights the critical role of vigilant post-surgical monitoring and comprehensive histopathological analysis following cholecystectomy, especially in areas with a higher incidence of gallbladder carcinoma. FNAC also plays a valuable diagnostic modality for early detection and management of Port site metastasis in unsuspected gallbladder carcinoma cases.