Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat · 2015
Assessment of patients with nasal polyposis by the neutrophil-to-lymphocyte ratio and eosinophil-to-lymphocyte ratio.
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Yenigün Alper
Аннотация
OBJECTIVES: This study aims to investigate the neutrophil-to-lymphocyte ratio (NLR) and eosinophil-to-lymphocyte ratio (ELR) levels in recurrent and non-recurrent nasal polyposis, and identify how the NLR and ELR reflect the inflammatory status in this specific diagnosis preoperatively.
PATIENTS AND METHODS: A total of 158 patients (102 males, 56 females; mean age 29.40±5.44 years; range 14 to 48 years) were included in the study. The patients were divided into two groups: group 1 included 80 recurrent nasal polyposis patients (44 males, 36 females; mean age 30.0±9.4 years; range 14 to 47 years) and group 2 included 78 non-recurrent nasal polyposis patients without allergic or atopic backgrounds (58 males, 20 females; mean age 28.8±10.1 years; range 17 to 48 years). The NLR and ELR values for each patient were calculated from the complete blood counts taken before surgery. The values of preoperative white blood cell, neutrophil, lymphocyte, eosinophil, NLR and ELR were compared for each group, and also in between the two groups.
RESULTS: The preoperative neutrophil, eosinophil, NLR and ELR values of group 1 were significantly higher than group 2 (p=0.042, p=0.013, p=0.019, and p=0.0001 respectively).
CONCLUSION: Neutrophil-to-lymphocyte and ELR measurements can be used effectively in patients with nasal polyposis as an auxiliary method in deciding for the necessity of recurrence follow-ups.
PATIENTS AND METHODS: A total of 158 patients (102 males, 56 females; mean age 29.40±5.44 years; range 14 to 48 years) were included in the study. The patients were divided into two groups: group 1 included 80 recurrent nasal polyposis patients (44 males, 36 females; mean age 30.0±9.4 years; range 14 to 47 years) and group 2 included 78 non-recurrent nasal polyposis patients without allergic or atopic backgrounds (58 males, 20 females; mean age 28.8±10.1 years; range 17 to 48 years). The NLR and ELR values for each patient were calculated from the complete blood counts taken before surgery. The values of preoperative white blood cell, neutrophil, lymphocyte, eosinophil, NLR and ELR were compared for each group, and also in between the two groups.
RESULTS: The preoperative neutrophil, eosinophil, NLR and ELR values of group 1 were significantly higher than group 2 (p=0.042, p=0.013, p=0.019, and p=0.0001 respectively).
CONCLUSION: Neutrophil-to-lymphocyte and ELR measurements can be used effectively in patients with nasal polyposis as an auxiliary method in deciding for the necessity of recurrence follow-ups.