Eksperimental'naia i klinicheskaia farmakologiia · 2012
[Effect of some vitamins on activity of immunocompetent cells].
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Nezgovorov D V
Аннотация
The content of vitamins A, E, B1, B2, B6 in lymphocytes and serum of blood was studied with simultaneous determination of CD3+, CD5+, CD4+, CD8+, CD16+, CD25+, CD71+, CD95+, and HLADR+ populations. According to cellular immunity response, patients were divided into two groups--with physiological norm and deficiency. It was established that, irrespective of the group, the content of vitamins A, E, B6 in blood serum does not change, while the concentration of B1 and B2 in the group with physiological norm is greater than that in the group with deficiency. In the group with deficiency of cellular immunity, increased level of endocellular vitamins A, E, B2 and B6 was revealed. Concentration of thiamine in both blood serum and lymphocytes in the group with physiological norm was greater than in the group with deficiency of cellular immunity.