[The immunomodulating effect of vilozen and splenin in the treatment of patients with acute and chronic toxic-allergic hepatitis].

65 patients with acute hepatitis and 116 patients with chronic hepatitis of toxico-allergic nature were examined. 20 patients with acute hepatitis and 40 patients with chronic form of the disease were prescribed in addition to conventional treatment 2-4 ml i.m. of splenin daily, 20 mg of vilosen daily in 3-4 divided doses in the form of 1% solution intranasally and the same quantity--sublingually. The drugs were administered for 10-15 days. Co-administration of splenin and vilosen was established to hasten normalization of clinical indices and immune homeostasis restitution thus advocating the use of the drugs as a part of therapeutic complex in the treatment of acute and chronic toxico-allergic hepatitis.