A technique for continuous infusion into the mouse bladder.

A new technique is described for long term placement of an indwelling catheter into the mouse bladder. This technique allows the animal to void normally while receiving an intravesical infusion for several weeks. The presence of the catheter still enables MBT-2 tumor cells to implant into the bladder wall. This model will be useful for investigating the effect of various anticancer agents administered intravesically over prolonged periods of time.