Head & neck · 2025
Patient-Specific Cranio-Facial Porous Titanium Implants: A Multicentric Cohort Study.
СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Schouman Thomas, Benateau Herve, Le Clerc Nicolas, Talbi Marouane, Roualdes Vincent, Vives Pierre, Rao Jai P, Foy Jean-Philippe
Аннотация
OBJECTIVE: To investigate the clinical tolerance and performance of personalized porous titanium implants (PTIs) used on the craniofacial skeleton.
STUDY DESIGN: Retrospective study.
SETTING: International multicentric study.
METHODS: Adult patients who received PTIs during a 7-year period were included. The primary outcome was the presence of the PTI at the last visit without surgical revision. Local and systemic infections, implant removal, fixation device failure, exposure, re-intervention, and adverse events were assessed at the last visit. We also analyzed risk factors for implant failure.
RESULTS: Ninety patients (36, 33, and 21 in the skull, midface, and mandible groups, respectively) with 97 craniofacial PTIs were followed up for a mean of 2.46 years after surgery. At the last visit, 73 patients (81.1%) still had their implant. Overall success rates were 97.2%, 78.8%, and 57.1% for the skull, midface, and mandible groups, respectively. Most complications and implant removals occurred in the mandible group and irradiated patients. On the whole cohort, radiotherapy was associated with a > 4-time higher risk of failure.
CONCLUSION: This study demonstrated an acceptable PTIs overall benefit-risk profile. However, we recommend a careful selection of patients, taking into account anatomical site and treatment history.
STUDY DESIGN: Retrospective study.
SETTING: International multicentric study.
METHODS: Adult patients who received PTIs during a 7-year period were included. The primary outcome was the presence of the PTI at the last visit without surgical revision. Local and systemic infections, implant removal, fixation device failure, exposure, re-intervention, and adverse events were assessed at the last visit. We also analyzed risk factors for implant failure.
RESULTS: Ninety patients (36, 33, and 21 in the skull, midface, and mandible groups, respectively) with 97 craniofacial PTIs were followed up for a mean of 2.46 years after surgery. At the last visit, 73 patients (81.1%) still had their implant. Overall success rates were 97.2%, 78.8%, and 57.1% for the skull, midface, and mandible groups, respectively. Most complications and implant removals occurred in the mandible group and irradiated patients. On the whole cohort, radiotherapy was associated with a > 4-time higher risk of failure.
CONCLUSION: This study demonstrated an acceptable PTIs overall benefit-risk profile. However, we recommend a careful selection of patients, taking into account anatomical site and treatment history.