Archives of virology · 2010
Completion of the full-length genome sequence of human parainfluenza virus types 4A and 4B: sequence analysis of the large protein genes and gene start, intergenic and end sequences.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Komada Hiroshi, Kawano Mitsuo, Uefuji Atsuo, Ito Morihiro, Tsurudome Masato, Hatakeyama Eri, Nakanishi Mai, Sakue Shiho, Joh Chika, Suzumura Eriko, Tamaki Tatsuya, Tomioka Toshifumi, Nishio Machiko, Tsumura Hideki, Uematsu Jun, Yamamoto Hidetaka, O'Brien Myles, Bando Hisanori, Ito Yasuhiko
Аннотация
We have already reported the nucleotide sequences of the NP, P/V, M, F and HN genes of human parainfluenza virus type 4A (hPIV-4A) and type 4B (hPIV-4B). Here, we have determined the sequences of the L protein genes as well as the gene start, intergenic and end sequences, thereby completing the full-length genome sequence of hPIV-4A and 4B. hPIV-4A and 4B have 17,052 and 17,304 nucleotides, respectively. The end sequence of hPIV-4, especially 4B, was extraordinarily long. In a comparison with members of the genus Rubulavirus, the hPIV-4 L proteins were closely related to those of mumps virus (MUV) and hPIV-2, less closely related to those of Menangle virus and Tioman virus, and more distantly related to those of Mapuera virus and porcine rubulavirus.