Heart & lung : the journal of critical care · 2015
The effect of race on long term mortality in mechanically ventilated patients.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Kaya Hatice, Rider Katherine E B, Amdur Richard L, Wulf-Gutierrez Marian, Smith Jessica A, Al Ghamdi Abdullah, Maximos Robert B, Das Aparna, Beyzaei-Arani Arshan, Ballarino Guillermo, Türkan Hülya, Bargoty Bashar, Ahari Jalil, Gutierrez Guillermo
Аннотация
OBJECTIVE: Determine the impact of race on one-year mortality following mechanical ventilation.
BACKGROUND: There is a lack of prospective studies on the effect of race on survival following mechanical ventilation.
METHODS: Observational study of adult patients on ventilatory support for <24 h prior to enrollment. Socioeconomic factors, laboratory and clinical data were recorded. Primary outcome was one-year mortality.
RESULTS: We enrolled 178 patients; 100 African American (AA), 78 other races (OTH). One-year mortality for AA was 49% and 33% for OTH (p = 0.035). After correcting for covariates, race was not significantly associated with mortality (p = 0.42). AA patients had higher mean arterial blood pressure, serum creatinine, heart rate, and peak (p < 0.01) and mean (p = 0.05) airway pressures.
CONCLUSIONS: AA patients who underwent mechanical ventilation had greater one-year mortality, although race per se was not a significant factor. It remains to be determined if strict blood pressure control and lower airway pressures may improve survival in this racial group.
BACKGROUND: There is a lack of prospective studies on the effect of race on survival following mechanical ventilation.
METHODS: Observational study of adult patients on ventilatory support for <24 h prior to enrollment. Socioeconomic factors, laboratory and clinical data were recorded. Primary outcome was one-year mortality.
RESULTS: We enrolled 178 patients; 100 African American (AA), 78 other races (OTH). One-year mortality for AA was 49% and 33% for OTH (p = 0.035). After correcting for covariates, race was not significantly associated with mortality (p = 0.42). AA patients had higher mean arterial blood pressure, serum creatinine, heart rate, and peak (p < 0.01) and mean (p = 0.05) airway pressures.
CONCLUSIONS: AA patients who underwent mechanical ventilation had greater one-year mortality, although race per se was not a significant factor. It remains to be determined if strict blood pressure control and lower airway pressures may improve survival in this racial group.