Internal medicine (Tokyo, Japan) · 2013
Two cases of acute respiratory distress syndrome with high values of Chlamydophila pneumoniae-specific antibodies.
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Igusa Ryotaro, Nakamura Atsushi, Kawana Sachiko, Shibahara Taizou, Narumi Sodai, Oikawa Takuya, Yoshida Kazunori, Kobayashi Takafumi, Ota Kozo
Аннотация
We herein report two cases of acute respiratory distress syndrome (ARDS) with high values of Chlamydophila pneumoniae-specific antibodies. In the first case (a 65-year-old man), high levels of anti-C. pneumoniae antibodies (IgG and IgA) were detected on admission, and the anti-C. pneumoniae IgA level rose by Day 30. The patient was successfully treated with quinolone and steroids. In the second case (an 85-year-old man), abnormally high levels of anti-C. pneumoniae IgM were detected on admission. The patient did not recover, despite receiving treatment with several antibiotics and anti-inflammatory agents. Neither of the patients displayed other pathogen-specific antigens or antibodies. Chlamydophila pneumonia is usually mild, although it can cause severe interstitial pneumonia and ARDS in reinfected patients and the elderly.