Outcomes in Children With Enterovirus Meningitis in London, England: A Retrospective Multicenter Cohort Study, 2013-2023.

Nonpolio enteroviruses are the most common cause of meningitis in children. We conducted a retrospective case series of long-term outcomes in 243 children between 1 January 2013 and 31 December 2023 across 4 tertiary centers in London. Adverse outcomes were associated with the absence of fever at presentation (odds ratio [OR], 4.65; 95% CI, 1.03-20.83), the presence of seizures (OR, 7.40; 95% CI, 1.05-51.96), and the presence of comorbidities at baseline (OR, 5.27; 95% CI, 1.18-23.47). Full recovery was seen in 153 of 160 (95.6%) children who were <3 months of age. These data may help clinicians to counsel parents and policy makers on streamlining care pathways following hospital discharge.