Diagnostic microbiology and infectious disease · 2023
Secondary Klebsiella pneumoniae infection in patients with COVID-19: A systematic review.
Систематический обзорСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Koupaei Maryam, Asadi Arezoo, Mahdizade Ari Marzie, Seyyedi Zahra Sadat, Mohammadi Fahime, Afifi Rad Roghayeh, Ghanavati Roya, Rezaei Khozani Nahid, Darbandi Atieh, Masjedian Jazi Faramarz
Аннотация
This study aims to investigate the development of secondary bacterial infection and risk factors associated with it in critical COVID-19 patients, and to identify the most common pathogen groups in them. All the cohort studies were retrieved from Scopus, Google Scholar, Web of Science, and MEDLINE from the inception of COVID-19 to 2022 for the following keywords: 'Klebsiella" AND "COVID-19". The most common comorbidities among the patients with COVID-19 were respiratory disease (33.62%), obesity (28.99%), and heart disease or cardiovascular disease (16.31%). We report 42.91% rate of Klebsiella spp co-infection in ICU admission patients, mostly related to K. pneumonia (26.81%), K. aerogenes (9.4%), and K. oxytoca (6.7%). The overall incidence of bacterial infection in hospitalized COVID-19 patients is estimated at 15.5% and in 32.5% of cases of co-infection patients deceased. The threat of carbapenem-resistant K. pneumoniae infections in patients with COVID-19 is imminent, therefore rational antibiotic therapy based on antibiotic sensitivity test should be implemented.