Treatment of women with generalized anxiety disorder during the postpartum period with paroxetine: A retrospective analysis of 11 years of clinical data.

We presented the results on the efficacy of paroxetine in postpartum women with generalized anxiety disorder (GAD) in current study. We included data on 33 patients to our study retrospectively. The patients were evaluated using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, the Clinical Global Impression-Improvement Scale, the Hamilton Depression rating Scale (HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A). The patients had significant improvement in both HAM-D and HAM-A scores following paroxetine treatment for 8 wk. The response and remission rates were 78.8 and 63.6%, respectively. Both rates were significantly higher the subgroup of patients without comorbid depression compared to patients with comorbid depression. Based on the findings of the present study, we suggest that paroxetine may be beneficial for in postpartum women with GAD.