Research for corresponding dental therapy for patients undergoing bone marrow and peripheral blood stem-cell transplantation.

In an interdisciplinary co-operation between the Haematology Department of the III. Medical Clinic, University of Mainz, and the Polyclinic for Restorative Dentistry Mainz, Germany, a total of 61 patients (33 men, 28 women, average age 43.2 +/- 11.5 years) received dental examination just before undergoing bone marrow transplantation (BMT) (n = 17) and peripheral blood stem-cell transplantation (PBSCT) (n = 44) respectively. The aim of this study was to determine the frequency of dentogenic complications during the aplasia phase. - Patients, who were scheduled for either bone marrow or blood stem-cell transplantation, have been examined in view of their serious susceptibility to infections during the aplasia phase, even though the probability of an exacerbation is said to be quite low, as it has been shown in the present study.