Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
Association of macular sensitivity with posterior staphyloma in highly myopic eyes: Aier-SERI high myopia adult cohort study.
СтатьяНаблюдательное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Jiang Yanfeng, Foo Li-Lian, Hu Ziqi, Pan Wei, Cheong Kai-Xiong, Tan Huanhuan, Saw Seang-Mei, Hoang Quan V, Yang Zhikuan, Lan Weizhong
Аннотация
PURPOSE: The purpose of this study was to determine the relationship between macular sensitivity (MS) and posterior staphyloma (PS) in highly myopic eyes.
METHODS: This cross-sectional, observational study included 646 highly myopic eyes (spherical equivalent (SE) ≤-5.00D and the international meta-analysis for pathologic myopia classification grade of <2) from 362 participants. MS was measured using microperimetry and evaluated between eyes with and without PS. Correlations between MS and PS were determined in multivariate regression models.
RESULTS: Although there was no significant difference in best-corrected visual acuity (BCVA) (p = 0.07), the MS of the PS group was significantly lower than the no PS group at the central 2°, 4°, 6°, 8° and 10° (all p < 0.001). After controlling age, axial length (AL) and SE, the MS in the PS group was still lower than the no PS group from 2° to 10° (all p < 0.05). In a multivariable analysis adjusting for age, AL, SE and BCVA, the presence of PS was significantly associated with lower MS in the central 2°-10° (all p < 0.05).
CONCLUSIONS: Lower MS was independently associated with the presence of PS in highly myopic eyes. Even when BCVA was not significantly different, MS still could reveal subtle changes in visual function in highly myopic eyes with PS.
METHODS: This cross-sectional, observational study included 646 highly myopic eyes (spherical equivalent (SE) ≤-5.00D and the international meta-analysis for pathologic myopia classification grade of <2) from 362 participants. MS was measured using microperimetry and evaluated between eyes with and without PS. Correlations between MS and PS were determined in multivariate regression models.
RESULTS: Although there was no significant difference in best-corrected visual acuity (BCVA) (p = 0.07), the MS of the PS group was significantly lower than the no PS group at the central 2°, 4°, 6°, 8° and 10° (all p < 0.001). After controlling age, axial length (AL) and SE, the MS in the PS group was still lower than the no PS group from 2° to 10° (all p < 0.05). In a multivariable analysis adjusting for age, AL, SE and BCVA, the presence of PS was significantly associated with lower MS in the central 2°-10° (all p < 0.05).
CONCLUSIONS: Lower MS was independently associated with the presence of PS in highly myopic eyes. Even when BCVA was not significantly different, MS still could reveal subtle changes in visual function in highly myopic eyes with PS.