Clinical and experimental nephrology · 2008
Late-onset and atypical presentation of Pneumocystis carinii pneumonia in a renal transplant recipient.
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Li Jordan Y Z, Yong Tuck Y, Grove David I, Coates P Toby H
Аннотация
Pneumocystis jivorecii (formerly known as carinii) pneumonia (PCP) is potentially a life-threatening opportunistic infection after organ transplantation, occurring most frequently in the first 12 months, where the incidence rate is several-fold higher than in later years. PCP typically presents with fever, cough, dyspnoea and hypoxia. In organ transplant recipients, the onset of symptoms is generally more fulminant compared to patients infected with the human immunodeficiency virus. We present a patient who developed PCP five years after a renal transplantation. His presentation was characterised by atypical symptoms and an indolent onset. Previous acute vascular rejection, ongoing maintenance prednisolone usage, cytomegalovirus seropositivity and past tuberculous infection may have predisposed this patient to PCP.
Предметные рубрики MeSH
Anti-Infective AgentsBronchoscopyCytomegalovirus InfectionsGraft RejectionHumansImmunosuppressive AgentsKidney TransplantationMaleMiddle AgedPleural EffusionPneumonia, PneumocystisPrednisoloneRadiography, ThoracicRisk FactorsTime FactorsTomography, X-Ray ComputedTreatment OutcomeTrimethoprim, Sulfamethoxazole Drug CombinationTuberculosis, Pulmonary