Irish journal of medical science · 2007
Pneumocystis carinii pneumonia in a patient on etanercept for psoriatic arthritis.
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Lahiff C, Khiaron O B, Nolan N, Chadwick G A
Аннотация
BACKGROUND: Pneumocystis carinii pneumonia (PCP) is a rare form of pneumonia associated with immune-suppression. It is common in patients with AIDS and with a CD4 count of less than 200 cells/mm(3). We report a case of PCP secondary to immune-suppression in a 41-year-old man with psoriatic arthritis being treated with the immune-modulatory agent etanercept.
METHODS: Diagnosis of PCP was made histologically using tissue obtained via transbronchial biopsy.
RESULTS: There was a good response to standard treatment with high-dose co-trimoxazole.
CONCLUSION: This report highlights a recognised but previously unreported complication of etanercept.
METHODS: Diagnosis of PCP was made histologically using tissue obtained via transbronchial biopsy.
RESULTS: There was a good response to standard treatment with high-dose co-trimoxazole.
CONCLUSION: This report highlights a recognised but previously unreported complication of etanercept.
Предметные рубрики MeSH
AdultArthritis, PsoriaticBiopsy, NeedleEtanerceptFollow-Up StudiesHumansImmunoglobulin GImmunohistochemistryImmunosuppression TherapyImmunosuppressive AgentsMalePneumonia, PneumocystisReceptors, Tumor Necrosis FactorRisk AssessmentSeverity of Illness IndexTreatment OutcomeTrimethoprim, Sulfamethoxazole Drug Combination