Emerging biosensor technologies for obstructive sleep apnea: A comprehensive overview and future prospects.

Obstructive sleep apnea (OSA) is a pervasive disorder characterized by recurrent airway obstructions during sleep. OSA carries serious health risks, such as cardiovascular and cognitive impairments, and imposes a significant economic burden. This chapter provides a comprehensive overview of various biosensors currently employed for OSA detection, including in-lab polysomnography and flow-based home sleep apnea testing. It also explores cutting-edge OSA-detecting technologies that often leverage advanced, artificial intelligence-powered sensing modalities, encompassing photoplethysmography/peripheral arterial tonometry-based, sound-based, and respiratory effort-based wearables. Moreover, this chapter examines promising diagnostic and screening solutions, including airables, bed/mattress sensors, and smartphone sensors. It also delves into emerging sensing technologies currently under active investigation, including earables/hearables and remote PPG. This review serves as a practical guide to understanding the mechanisms, capabilities, limitations, and clinical evidence surrounding both modern and future sensors poised to revolutionize the landscape of OSA detection.