The Journal of laryngology and otology · 2011
Thyroid lymphoma: acute presentation and long-term outcome.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Penney S E, Homer J J
Аннотация
BACKGROUND: Thyroid lymphomas are relatively uncommon. This study aimed to analyse our experience of thyroid lymphoma management and outcome.
MATERIALS AND METHODS: A retrospective case note analysis of 63 patients treated in the previous 13 years was conducted.
RESULTS: The five-year survival rate was 68 per cent, with most patients dying of their lymphoma. This is at odds with the British Thyroid Association statement that the prognosis of this condition is 'generally excellent'. The only presenting symptom found to be significantly associated with prognosis was dysphagia (p = 0.001). Dual modality treatment provided a significantly better outcome than single modality treatment (p = 0.014). Thyroid lymphoma can present to the head and neck surgeon 'in extremis'; however, it can respond rapidly to appropriate treatment.
CONCLUSION: The outcome of thyroid lymphoma seems unrelated to the acuteness of its presentation. Thyroid surgery has no role other than for diagnosis. However, 51 per cent of the study patients underwent some form of thyroidectomy, indicating the need to implement better diagnostic pathways.
MATERIALS AND METHODS: A retrospective case note analysis of 63 patients treated in the previous 13 years was conducted.
RESULTS: The five-year survival rate was 68 per cent, with most patients dying of their lymphoma. This is at odds with the British Thyroid Association statement that the prognosis of this condition is 'generally excellent'. The only presenting symptom found to be significantly associated with prognosis was dysphagia (p = 0.001). Dual modality treatment provided a significantly better outcome than single modality treatment (p = 0.014). Thyroid lymphoma can present to the head and neck surgeon 'in extremis'; however, it can respond rapidly to appropriate treatment.
CONCLUSION: The outcome of thyroid lymphoma seems unrelated to the acuteness of its presentation. Thyroid surgery has no role other than for diagnosis. However, 51 per cent of the study patients underwent some form of thyroidectomy, indicating the need to implement better diagnostic pathways.
Предметные рубрики MeSH
Acute DiseaseAdultAge FactorsAgedAged, 80 and overAirway ObstructionBiopsyCombined Modality TherapyDeglutition DisordersDiagnosis, DifferentialFemaleHashimoto DiseaseHumansKaplan-Meier EstimateLymphoma, B-CellMaleMiddle AgedNeoplasm StagingPractice Guidelines as TopicPrognosisRecurrenceRetrospective StudiesSex DistributionSurvival RateThyroid NeoplasmsThyroidectomyTracheostomyTreatment OutcomeUnited Kingdom