European journal of neurology · 2011
Reduction in medication-overuse headache after short information. The Akershus study of chronic headache.
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Grande R B, Aaseth K, Benth J Š, Lundqvist C, Russell M B
Аннотация
OBJECTIVE: our aim was to investigate the course of medication-overuse headache in the general population and the effect of simple advice regarding medication overuse.
DESIGN: prospective cohort study. Participants were identified in a cross-sectional epidemiological sample of 30000 persons aged 30-44 from the general Norwegian population. People with chronic headache (≥ 15 days per month for at least 3 months) and medication overuse received short information about the possible role of medication overuse in headache chronification. A cohort was followed up 1½ years later. The diagnostic criteria of the International Classification of Headache Disorders and data splitting methodology were used.
SETTING: Akershus University Hospital, Oslo, Norway.
PARTICIPANTS: a total of 109 participants with chronic primary headache and medication overuse were available for follow-up (85% participation rate).
MAIN OUTCOME MEASURE: Change in medication days and headache days per month.
RESULTS: at baseline chronic tension-type headache was found in 92% of participants; 8% had chronic migraine or new daily persistent headache. Migraine co-occurrence was found in 53%. The mean duration of chronic headaches were 8-18 years, the mean duration of medication overuse between 5 and 10 years prior to intervention. At follow up, the mean medication days were significantly reduced from 22 days to 6 days per month, and 76% no longer had medication overuse. Forty-two percent no longer had chronic headache and the headache index was reduced by 24%.
CONCLUSION: our examination and short information served as a modified brief intervention which can improve chronic headache and medication overuse in the general population.
DESIGN: prospective cohort study. Participants were identified in a cross-sectional epidemiological sample of 30000 persons aged 30-44 from the general Norwegian population. People with chronic headache (≥ 15 days per month for at least 3 months) and medication overuse received short information about the possible role of medication overuse in headache chronification. A cohort was followed up 1½ years later. The diagnostic criteria of the International Classification of Headache Disorders and data splitting methodology were used.
SETTING: Akershus University Hospital, Oslo, Norway.
PARTICIPANTS: a total of 109 participants with chronic primary headache and medication overuse were available for follow-up (85% participation rate).
MAIN OUTCOME MEASURE: Change in medication days and headache days per month.
RESULTS: at baseline chronic tension-type headache was found in 92% of participants; 8% had chronic migraine or new daily persistent headache. Migraine co-occurrence was found in 53%. The mean duration of chronic headaches were 8-18 years, the mean duration of medication overuse between 5 and 10 years prior to intervention. At follow up, the mean medication days were significantly reduced from 22 days to 6 days per month, and 76% no longer had medication overuse. Forty-two percent no longer had chronic headache and the headache index was reduced by 24%.
CONCLUSION: our examination and short information served as a modified brief intervention which can improve chronic headache and medication overuse in the general population.