Cephalalgia : an international journal of headache · 2010
Guidelines for controlled trials of drugs in tension-type headache: second edition.
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Bendtsen L, Bigal M E, Cerbo R, Diener H C, Holroyd K, Lampl C, Mitsikostas D D, Steiner T J, Tfelt-Hansen P, International Headache Society Clinical Trials Subcommittee
Аннотация
The Clinical Trials Subcommittee of the International Headache Society published its first edition of the guidelines on controlled trials of drugs in tension-type headache in 1995. These aimed 'to improve the quality of controlled clinical trials in tension-type headache', because 'good quality controlled trials are the only way to convincingly demonstrate the efficacy of a drug, and form the basis for international agreement on drug therapy'. The Committee published similar guidelines for clinical trials in migraine and cluster headache. Since 1995 several studies on the treatment of episodic and chronic tension-type headache have been published, providing new information on trial methodology for this disorder. Furthermore, the classification of the headaches, including tension-type headache, has been revised. These developments support the need for also revising the guidelines for drug treatments in tension-type headache. These Guidelines are intended to assist in the design of well-controlled clinical trials in tension-type headache.