Comparing the effectiveness of clomipramine and fluoxetine in dogs with anxiety-related behaviours.

PICO QUESTION: In dogs with anxious behaviours, is fluoxetine more effective than clomipramine in reducing anxiety-related behaviours?

CATEGORY OF RESEARCH: Treatment.

NUMBER AND TYPE OF STUDY DESIGNS REVIEWED: Three controlled studies were critically appraised.

STRENGTH OF EVIDENCE: Moderate.

OUTCOMES REPORTED: Administration of either fluoxetine or clomipramine to adult dogs reduces symptoms of fear and anxiety.

CONCLUSION

Both fluoxetine and clomipramine are effective in reducing acral lick dermatitis and tail chasing behaviours, but there is no evidence that one drug is more effective than the other.