Journal of clinical medicine · 2022
Efficacy and Toxicity of Classical Immunosuppressants, Retinoids and Biologics in Hidradenitis Suppurativa.
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Das Kinnor, Daveluy Steven, Kroumpouzos George, Agarwal Komal, Podder Indrashis, Farnbach Katherine, Ortega-Loayza Alex G, Szepietowski Jacek C, Grabbe Stephan, Goldust Mohamad
Аннотация
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the apocrine glands characterized by recurrent episodes. Although several therapies exist, none is completely curative. Several immunosuppressives have been studied with encouraging results and targeted approaches. In this review, we highlight the various immunosuppressives used in this condition along with their salient features to enable physicians to choose the correct therapy for their patients. The search of the peer-reviewed literature included clinical trials, scientific reviews, case series, case reports, and guidelines. The literature was identified from electronic databases (MEDLINE and PubMed) through November 2021; additional articles were included from the references of the identified articles.