Klinika oczna · 1998
[The effect of selenium and vitamin E on the healing process of experimental corneal lesions in the eye of the rabbit].
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Sieradzki E, Olejarz E, Strauss K, Marzec A, Mieszkowska M, Kałuzny J
Аннотация
PURPOSE: Evaluation of antioxidants: selenium and vitamin E efficacy in the treatment of experimental corneal lesion.
MATERIAL AND METHODS: Solution of selenium in 0.9% NaCl, concentration 0.01 g/L, to which vitamin E was added to obtain suspension of 2.5 g/L was used in 9 rabbits. The cornea was damaged by removing the epithelium from the central area of 7 mm diameter. To the right eye selenium solution with vitamin E was instilled.
RESULTS: In two eyes in which antioxidants were used evident prompt healing of corneal ulceration was noticed. Mean lesion diameter in eyes treated with antioxidants was: on 1st day 5.44 mm, in 2nd day 1.61 mm and on the 3rd day 0.33 mm. In control eyes diameters were: 6.67 mm, 2.28 mm and 0.56 mm, respectively.
CONCLUSIONS: Solution used in our study was tolerated very well. Faster healing process was noticed in eyes where antioxidants were used.
MATERIAL AND METHODS: Solution of selenium in 0.9% NaCl, concentration 0.01 g/L, to which vitamin E was added to obtain suspension of 2.5 g/L was used in 9 rabbits. The cornea was damaged by removing the epithelium from the central area of 7 mm diameter. To the right eye selenium solution with vitamin E was instilled.
RESULTS: In two eyes in which antioxidants were used evident prompt healing of corneal ulceration was noticed. Mean lesion diameter in eyes treated with antioxidants was: on 1st day 5.44 mm, in 2nd day 1.61 mm and on the 3rd day 0.33 mm. In control eyes diameters were: 6.67 mm, 2.28 mm and 0.56 mm, respectively.
CONCLUSIONS: Solution used in our study was tolerated very well. Faster healing process was noticed in eyes where antioxidants were used.