Pneumonia Caused by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza Virus: A Multicenter Comparative Study.
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Oi Issei, Ito Isao, Hirabayashi Masataka, Endo Kazuo, Emura Masahito, Kojima Toru, Tsukao Hitokazu, Tomii Keisuke, Nakagawa Atsushi, Otsuka Kojiro, Akai Masaya, Oi Masahiro, Sugita Takakazu, Fukui Motonari, Inoue Daiki, Hasegawa Yoshinori, Takahashi Kenichi, Yasui Hiroaki, Fujita Kohei, Ishida Tadashi, Ito Akihiro, Kita Hideo, Kaji Yusuke, Tsuchiya Michiko, Tomioka Hiromi, Yamada Takashi, Terada Satoru, Nakaji Hitoshi, Hamao Nobuyoshi, Shirata Masahiro, Nishioka Kensuke, Yamazoe Masatoshi, Shiraishi Yusuke, Ogimoto Tatsuya, Hosoya Kazutaka, Ajimizu Hitomi, Shima Hiroshi, Matsumoto Hisako, Tanabe Naoya, Hirai Toyohiro
Аннотация
METHODS: A prospective, multicenter cohort study was conducted by including patients with CP who were hospitalized between January and June 2020 and a retrospective cohort of patients with IP hospitalized from 2009 to 2020. We compared the clinical presentations and studied the prognostic factors of CP and IP.
RESULTS: Compared with the IP group (n = 66), in the multivariate analysis, the CP group (n = 362) had a lower percentage of patients with underlying asthma or chronic obstructive pulmonary disease (P < .01), lower neutrophil-to-lymphocyte ratio (P < .01), lower systolic blood pressure (P < .01), higher diastolic blood pressure (P < .01), lower aspartate aminotransferase level (P < .05), higher serum sodium level (P < .05), and more frequent multilobar infiltrates (P < .05). The diagnostic scoring system based on these findings showed excellent differentiation between CP and IP (area under the receiver operating characteristic curve, 0.889). Moreover, the prognostic predictors were different between CP and IP.
CONCLUSIONS: Comprehensive differences between CP and IP were revealed, highlighting the need for early differentiation between these 2 pneumonias in clinical settings.