The Impact of Vaccination Among Hospitalized Patients with the Diagnosis of COVID-19.
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Yıldız Yeşim, Özger Hasan Selçuk, Acar Ali, Seremet-Keskin Ayşegül, Binay Umut Devrim, Ünlü Gülten, Bayram Halim, Asan Ali, Akça Mustafa Özgür, Karamanlioğlu Dilek, İnan Osman, Kaya Şafak, Yıldırım Çiğdem, Arslan Yusuf, Kömür Süheyla, Saygıdeğer Yasemin, Kandemir Fatma Özlem, Yaşar Simge, Akdemir-Kalkan İrem, Tekin-Taş Zeynep, Sakız Ayşe, Bayındır Yaşar, Özer Ayşe Belin, Mete Ayşe Özlem, Erol Çiğdem, Mermutluoğlu Çiğdem, Kadiroğlu Ali Kemal, Azap Alpay, Şenol Esin, Adult Immunization Study Group of the Turkish Society of Clinical Microbiology and Infectious Diseases
Аннотация
MATERIALS AND METHODS: This multi-center point-prevalence study was conducted on inpatients, divided into two groups as 'fully' and 'partially' vaccinated according to COVID-19 vaccination status.
RESULTS: Totally 516 patients were included in the study. The median age was 65 (55-77), and 53.5% (n=276) of the patients were male. Hypertension (41.9%, n=216), diabetes mellitus (DM) (31.8%, n=164), and coronary artery disease (CAD) (16.3%, n=84) were the predominant comorbidities. Patients were divided into two groups ICU (n=196) and non-ICU (n=301). Hypertension (p=0.026), DM (p=0.048), and congestive heart failure (CHF) (p=0.005) were significantly higher in ICU patients and the median age was younger among non-ICU patients (p=0.033). Of patients, 16.9% (n=87) were fully vaccinated, and this group's need for ICU support was statistically significantly lower (p=0.021).
CONCLUSION: We conclude that older age, hypertension, DM, CHF, and being partially vaccinated were associated with the need for ICU support. Therefore, all countries should continuously monitor post-vaccination breakthrough COVID-19 infections to determine the national booster vaccine administration approach that will provide vulnerable individuals the highest protection.