Plain Language Summary of Publication: Design of the Global Prospective Hemolytic Disease of the Fetus and Newborn Registry (GERANIUM).

This article is a plain language summary of publication (PLSP) of the following article: "Study Design of the Global Prospective Hemolytic Disease of the Fetus and Newborn Registry (GERANIUM)" by Tjoa et al published by the American Journal of Perinatology on March 20, 2026. This PLSP describes the design of the GERANIUM registry, which will collect data to help researchers understand how doctors manage hemolytic disease of the fetus and newborn (HDFN) in clinical settings. Researchers will also study outcomes related to the health and well-being of pregnant participants affected by HDFN, their children, and their families over time. This PLSP aims to help the general public, including those affected by HDFN, and health care professionals understand the design of the GERANIUM registry. · Data reflecting today's clinical care of HDFN are lacking.. · GERANIUM is a registry collecting real-world data on HDFN.. · Design of the GERANIUM registry is described.. · HDFN-related outcomes are collected during pregnancy.. · Infant outcomes will be recorded up to 2 years after birth..