[Correlation of changes in various enzymologic and immunologic indices and electrocardiotopographic findings in myocardial infarction complicated by true cardiogenic shock and acute left ventricular failure].

A total of 112 myocardial infarction survivors with the uncomplicated and the complicated (genuine cardiogenic shock, acute left ventricular insufficiency) course of the disease were followed up to study and correlate the activity of creatine phosphokinase (CPK), its MB isoenzyme, titres of the complement binding antibodies to CPK and the cardiac muscle and also electrocardiotopographic parameters. The time of the appearance, maximum elevation and normalization of the parameters under study did not depend on the presence or absence of complications. Genuine cardiogenic shock was characterized by higher values of CPK, MB CPK, as well as by a greater extent and depth of the necrotic and peri-infarction zones, as judged by the electrocardiotopogram , and lower increase in the titres of antibodies to CPK and the myocardium. Acute left ventricular insufficiency was associated with higher CPK activity and more elevated titres of antibodies to the latter with the greater extent and depth of the ischemic lesion as compared to the necrotic one. Significantly enhanced enzymic levels in the first case were of cardiac and in the second of extracardiac origin.