Indian pediatrics · 2018
Peripheral Precocious Puberty Caused by Human Chorionic Gonadotropin Producing Pineal Gland Tumor.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Hammadur Rahaman S K, Khandelwal Deepak, Khadgawat Rajesh, Kandasamy Devasenathipathy, Bakhshi Sameer
Аннотация
BACKGROUND: Pineal gland lesions usually present with central precocious puberty.
CASE CHARACTERISTICS: A 3½-yr-old boy presented with precocious puberty. Clinically and biochemically, it was gonadotropin releasing hormone (GnRH) independent. Serum and CSF beta-hCG levels were increased. Thin section magnetic resonance imaging of brain revealed a pineal gland tumor.
OUTCOME: He received chemotherapy followed by radiotherapy and responded well.
MESSAGE: CSF beta-hCG should be measured in all cases of peripheral precocity, and if CSF beta-hCG is elevated, thin section magnetic resonance imaging of brain should be considered.
CASE CHARACTERISTICS: A 3½-yr-old boy presented with precocious puberty. Clinically and biochemically, it was gonadotropin releasing hormone (GnRH) independent. Serum and CSF beta-hCG levels were increased. Thin section magnetic resonance imaging of brain revealed a pineal gland tumor.
OUTCOME: He received chemotherapy followed by radiotherapy and responded well.
MESSAGE: CSF beta-hCG should be measured in all cases of peripheral precocity, and if CSF beta-hCG is elevated, thin section magnetic resonance imaging of brain should be considered.