Safe, Repeated Treatment With Electroconvulsive Therapy in Combination With KarXT.

To our knowledge, no report has been made of safe concurrent treatment with the novel muscarinic antipsychotic agent KarXT and electroconvulsive therapy (ECT). The drug has the potential for influencing the ECT procedure as well as outcomes. These issues are explored in the context of a case in which KarXT and ECT were successfully combined safely and repeatedly.