Glaucoma disease diagnosis with an artificial algae-based deep learning algorithm.

Glaucoma disease is optic neuropathy; in glaucoma, the optic nerve is damaged because the long duration of intraocular pressure can be caused blindness. Nowadays, deep learning classification algorithms are widely used to diagnose various diseases. However, in general, the training of deep learning algorithms is carried out by traditional gradient-based learning techniques that converge slowly and are highly likely to fall to the local minimum. In this study, we proposed a novel decision support system based on deep learning to diagnose glaucoma. The proposed system has two stages. In the first stage, the preprocessing of glaucoma disease data is performed by normalization and mean absolute deviation method, and in the second stage, the training of the deep learning is made by the artificial algae optimization algorithm. The proposed system is compared to traditional gradient-based deep learning and deep learning trained with other optimization algorithms like genetic algorithm, particle swarm optimization, bat algorithm, salp swarm algorithm, and equilibrium optimizer. Furthermore, the proposed system is compared to the state-of-the-art algorithms proposed for the glaucoma detection. The proposed system has outperformed other algorithms in terms of classification accuracy, recall, precision, false positive rate, and F1-measure by 0.9815, 0.9795, 0.9835, 0.0165, and 0.9815, respectively.