Dental Therapeutic Applications of Nanotechnology and Artificial Intelligence (AI).

The integration of nanotechnology and artificial intelligence (AI) in dentistry offers transformative potential for diagnostics, treatment, and prevention. Guided by AI, nanobots can deliver targeted anesthesia, enhance caries prevention strategies, and support orthodontic realignment, whereas advances in nanotechnology simultaneously optimize dental materials and enable more personalized care. To realize this potential, however, challenges ranging from cost and toxicity to data limitations must be addressed. Although some applications (eg, diagnostic nanoparticles) are closer to clinical use, others (eg, fully autonomous nanobots) remain theoretic. Ongoing research and ethical considerations will shape the future of nanodentistry, revolutionizing oral health care if responsibly developed.