Journal of psychopharmacology (Oxford, England) · 2007
Panic and hypertension: brothers in arms through 5-HT?
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Davies S J, Lowry C A, Nutt D J
Аннотация
OBJECTIVE: To explore the contribution of carer characteristics, activities and disease impact to care burden and health in the multiple sclerosis caregiver population.
DESIGN: A prospective postal survey (24 months).
SETTING: The study was conducted in seven treatment centres within England.
SUBJECTS: Two hundred and fifty-seven caregivers of people with multiple sclerosis.
MEASURES: Carer activity, the Caregivers Reaction Assessment Scale (CRA), the Short Form General Health Survey (SF-36), version 2, and care-related health problems. The carer data were linked to a comprehensive patient data set which permitted dyadic variables to be created measuring shared health.
RESULTS: Carers were engaged in a wide spectrum of physical care activities; lifting was the most frequent, 74% (n = 192). Patient disease impact scores were positively correlated (P < 0.01) with higher carer activity levels (r = 0.66). The carer activity level increased over time (P < 0.001 ) by around 5% with a mean increase of 0.22 (95% confidence interval (CI) 0.12-0.3) in the carer activity summary score (scale 0-4). Disease impact was negatively correlated (P < 0.01) with carer burden r = - 0.44 (CRA composite scale), physical health status r = -0.27 (SF-36 physical component score) and mental health status r = - 0.21 (SF-36 mental component score); and positively correlated with care-related health problems r = 0.44. Hierarchical regression models explaining 39% and 49% of the variance in care burden and health problem respectively showed that disease impact and dyadic health explained most of the variance, with carer activity contributing an additional 2% to 4% of the variance (P < 0.001).
CONCLUSION: The analysis demonstrated that greater disease impact, lower dyadic health, high carer activity and greater carer burden are related to the level of carer-related health problems. The data suggested the need to develop interventions for assessing carers and reducing their activity levels and care burden (objective and subjective).
DESIGN: A prospective postal survey (24 months).
SETTING: The study was conducted in seven treatment centres within England.
SUBJECTS: Two hundred and fifty-seven caregivers of people with multiple sclerosis.
MEASURES: Carer activity, the Caregivers Reaction Assessment Scale (CRA), the Short Form General Health Survey (SF-36), version 2, and care-related health problems. The carer data were linked to a comprehensive patient data set which permitted dyadic variables to be created measuring shared health.
RESULTS: Carers were engaged in a wide spectrum of physical care activities; lifting was the most frequent, 74% (n = 192). Patient disease impact scores were positively correlated (P < 0.01) with higher carer activity levels (r = 0.66). The carer activity level increased over time (P < 0.001 ) by around 5% with a mean increase of 0.22 (95% confidence interval (CI) 0.12-0.3) in the carer activity summary score (scale 0-4). Disease impact was negatively correlated (P < 0.01) with carer burden r = - 0.44 (CRA composite scale), physical health status r = -0.27 (SF-36 physical component score) and mental health status r = - 0.21 (SF-36 mental component score); and positively correlated with care-related health problems r = 0.44. Hierarchical regression models explaining 39% and 49% of the variance in care burden and health problem respectively showed that disease impact and dyadic health explained most of the variance, with carer activity contributing an additional 2% to 4% of the variance (P < 0.001).
CONCLUSION: The analysis demonstrated that greater disease impact, lower dyadic health, high carer activity and greater carer burden are related to the level of carer-related health problems. The data suggested the need to develop interventions for assessing carers and reducing their activity levels and care burden (objective and subjective).