Prevalence of Trismus and its Effects on Quality of Life in Patients Treated for Oral Squamous Cell Carcinoma: A Prospective Study.

BACKGROUND

Trismus, a common complication of oral squamous cell carcinoma (OSCC) treatment, can significantly affect patients' quality of life (QoL). Understanding its prevalence and impact is crucial for improving patient care.

OBJECTIVE

To evaluate the prevalence of trismus and its effects on QoL in patients undergoing treatment for OSCC.

MATERIALS AND

METHODS

This prospective research involved 150 OSCC patients undergoing surgery, radiotherapy, or combined therapy. Trismus was defined as maximum interincisal opening (MIO) ≤35 mm, measured at baseline, 3, and 6 months post-treatment. QoL was estimated using the EORTC QLQ-C30 and QLQ-H and N35 questionnaires.

RESULTS

Trismus prevalence was 28% at baseline, increasing to 55% at 3 months and 47% at 6 months. Patients with trismus had significantly lower QoL scores in domains such as pain, emotional well-being, and social interactions.

CONCLUSION

Trismus is highly prevalent in OSCC patients and profoundly impacts QoL, highlighting the need for early interventions and targeted rehabilitation strategies.