Fertility and sterility · 2007
Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle.
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Mavroudis Konstantinos, Aloumanis Kyriakos, Papapetrou Peter D, Voros Dionisios, Spanos Iraklis
Аннотация
OBJECTIVE: Virilization due to androgen-secreting neoplasms in women is a result of androgen overproduction from benign or malignant tumors that are found in the ovaries or rarely in the adrenal glands. Virilizing tumors that arise from ectopic adrenal tissue are extremely rare. We describe a very rare case of an ectopic androgen-producing adrenal tumor.
DESIGN: Case report study.
SETTING: Endocrinology outpatient department of university-affiliated teaching hospital.
PATIENT(S): A 45-year-old woman with symptoms of virilization of abrupt onset and rapid progression, with high serum androgen hormone levels and normal glucocorticoid secretion.
INTERVENTION(S): Basal hormonal levels, stimulation and suppression tests, imaging techniques, and selective venous sampling.
MAIN OUTCOME MEASURE(S): Localization and surgical removal of the source of androgen production.
RESULT(S): An ectopic mass was detected behind the left iliopsoas muscle. The patient was operated on and an oblong-shaped lesion, weighing 6 g, was removed. Histologically, the tissue was identified to be of adrenal origin. Postoperatively the androgen levels decreased to normal levels.
CONCLUSION(S): This case illustrates difficulties in detecting and localizing the rare contingence of an ectopic adrenocortical androgen-secreting tumor.
DESIGN: Case report study.
SETTING: Endocrinology outpatient department of university-affiliated teaching hospital.
PATIENT(S): A 45-year-old woman with symptoms of virilization of abrupt onset and rapid progression, with high serum androgen hormone levels and normal glucocorticoid secretion.
INTERVENTION(S): Basal hormonal levels, stimulation and suppression tests, imaging techniques, and selective venous sampling.
MAIN OUTCOME MEASURE(S): Localization and surgical removal of the source of androgen production.
RESULT(S): An ectopic mass was detected behind the left iliopsoas muscle. The patient was operated on and an oblong-shaped lesion, weighing 6 g, was removed. Histologically, the tissue was identified to be of adrenal origin. Postoperatively the androgen levels decreased to normal levels.
CONCLUSION(S): This case illustrates difficulties in detecting and localizing the rare contingence of an ectopic adrenocortical androgen-secreting tumor.