[Pemphigoid diseases. Autoimmune diseases in the elderly].

BACKGROUND

The incidence and thereby also the relevance of pemphigoid diseases have significantly increased in elderly patients.

METHODS

The clinical features, diagnostic workup, and therapy of pemphigoid diseases based on the recently published German guidelines and expert opinions are described.

RESULTS

The diagnosis is based on medical history, clinical manifestations, histopathology, and autoimmune serology. Treatment options depend on the diagnosis and disease severity. Both local and systemic immunosuppressive or immunomodulatory strategies have been proven to be effective.

CONCLUSIONS

Chronic, itchy, inflammatory skin disorders in elderly patients are generally suspicious for pemphigoid diseases. The prognosis is usually good. For decisions about (local or systemic) immunosuppressive therapy, gerontological aspects should be taken into consideration.