B-ENT · 2012
Mean platelet volume in patients with nasal polyposis.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Sagit M, Cetinkaya S, Dogan M, Bayram A, Vurdem U E, Somdas M A
Аннотация
OBJECTIVE: To investigate whether mean platelet volume (MPV) levels rise in patients with nasal polyposis (NP) and whether higher MPV levels are correlated to the extension of polyps in these patients.
MATERIALS AND METHODS: This study included 50 patients with NP and 40 age- and sex-matched healthy subjects as controls. The Lund-Mackay staging system was used to assess paranasal sinus computed tomography (CT) scans in patients with NP, and paranasal sinus CT scores were recorded. MPV was measured in a blood sample collected in EDTA tubes and was also used for whole blood counts in all patients. The Mann-Whitney U-test and Student's t-test were used to compare the results of the two groups.
RESULTS: NP patients had higher MPV levels than the control group (9.60 +/- 1.06 fl and 8.77 +/- 0.88 fl, p < 0.001 respectively). However, there was no significant correlation between MPV and paranasal sinus CT scores.
CONCLUSION: To our knowledge, this is the first study to investigate MPV levels in patients with NP. Our results suggest that MPV, a determinant of platelet activation, is elevated in patients with NP. Increased platelet activation may be related to an increase in cardiovascular risk in patients with NP.
MATERIALS AND METHODS: This study included 50 patients with NP and 40 age- and sex-matched healthy subjects as controls. The Lund-Mackay staging system was used to assess paranasal sinus computed tomography (CT) scans in patients with NP, and paranasal sinus CT scores were recorded. MPV was measured in a blood sample collected in EDTA tubes and was also used for whole blood counts in all patients. The Mann-Whitney U-test and Student's t-test were used to compare the results of the two groups.
RESULTS: NP patients had higher MPV levels than the control group (9.60 +/- 1.06 fl and 8.77 +/- 0.88 fl, p < 0.001 respectively). However, there was no significant correlation between MPV and paranasal sinus CT scores.
CONCLUSION: To our knowledge, this is the first study to investigate MPV levels in patients with NP. Our results suggest that MPV, a determinant of platelet activation, is elevated in patients with NP. Increased platelet activation may be related to an increase in cardiovascular risk in patients with NP.