[Serum allergen-specific IgE in patients with eosinophilic nasal polyps].

OBJECTIVE

To investigate the relationship between airborne allergen and patients with nasal polyps (NP).

METHOD: Eighty-three cases of patients with NP were classified into the eosinophilic group(ENP) and non eosinophilic group (nENP) in terms of the EOS count in NP specimen, all patients underwent specific-IgE test with standardized allergens and the results were analyzed.

RESULT: The specific-IgE positive rate was 59.26% in ENP group and 23.21% in the nENP group respectively (P < 0.01), and the positive rate of ENP was statistical significance compared with nENP. The dust mite was the most prevalent airborne allergen in ENP group.

CONCLUSION

The perennial airborne allergens may play a certain role in the etiology and pathogenesis of NP.