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DOI 10.7326/m16-0317

Медицинская библиотека · Annals of internal medicine · 2016

Performance of the Tobacco, Alcohol, Prescription Medication, and Other Substance Use (TAPS) Tool for Substance Use Screening in Primary Care Patients.

McNeely Jennifer, Wu Li-Tzy, Subramaniam Geetha, Sharma Gaurav, Cathers Lauretta A, Svikis Dace, Sleiter Luke, Russell Linnea, Nordeck Courtney, Sharma Anjalee, O'Grady Kevin E, Bouk Leah B, Cushing Carol, King Jacqueline, Wahle Aimee, Schwartz Robert P

Клиническое исследованиеСтатьяМногоцентровое исследованиеПеревод пока не подготовлен

Аннотация

BACKGROUND

Substance use, a leading cause of illness and death, is underidentified in medical practice.

OBJECTIVE

The Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS) tool was developed to address the need for a brief screening and assessment instrument that includes all commonly used substances and fits into clinical workflows. The goal of this study was to assess the performance of the TAPS tool in primary care patients.

DESIGN

Multisite study, conducted within the National Drug Abuse Treatment Clinical Trials Network, comparing the TAPS tool with a reference standard measure. (ClinicalTrials.gov: NCT02110693).

SETTING

5 adult primary care clinics.

PARTICIPANTS

2000 adult patients consecutively recruited from clinic waiting areas.

MEASUREMENTS: Interviewer- and self-administered versions of the TAPS tool were compared with a reference standard, the modified World Mental Health Composite International Diagnostic Interview (CIDI), which measures problem use and substance use disorder (SUD).

RESULTS

Interviewer- and self-administered versions of the TAPS tool had similar diagnostic characteristics. For identifying problem use (at a cutoff of 1+), the TAPS tool had a sensitivity of 0.93 (95% CI, 0.90 to 0.95) and specificity of 0.87 (CI, 0.85 to 0.89) for tobacco and a sensitivity of 0.74 (CI, 0.70 to 0.78) and specificity of 0.79 (CI, 0.76 to 0.81) for alcohol. For problem use of illicit and prescription drugs, sensitivity ranged from 0.82 (CI, 0.76 to 0.87) for marijuana to 0.63 (CI, 0.47 to 0.78) for sedatives; specificity was 0.93 or higher. For identifying any SUD (at a cutoff of 2+), sensitivity was lower.

LIMITATIONS: The low prevalence of some drug classes led to poor precision in some estimates. Research assistants were not blinded to participants' TAPS tool responses when they administered the CIDI.

CONCLUSION

In a diverse population of adult primary care patients, the TAPS tool detected clinically relevant problem substance use. Although it also may detect tobacco, alcohol, and marijuana use disorders, further refinement is needed before it can be recommended broadly for SUD screening.

PRIMARY FUNDING SOURCE: National Institute on Drug Abuse.

Для цитирования: McNeely Jennifer, Wu Li-Tzy, Subramaniam Geetha, Sharma Gaurav, Cathers Lauretta A, Svikis Dace, Sleiter Luke, Russell Linnea, Nordeck Courtney, Sharma Anjalee, O'Grady Kevin E, Bouk Leah B, Cushing Carol, King Jacqueline, Wahle Aimee, Schwartz Robert P. Performance of the Tobacco, Alcohol, Prescription Medication, and Other Substance Use (TAPS) Tool for Substance Use Screening in Primary Care Patients.. Annals of internal medicine. 2016. DOI: 10.7326/m16-0317.

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