Retinal cases & brief reports · 2026
POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY FEATURES OF THE REPAIR TISSUE AFTER RETINAL PIGMENT EPITHELIUM TEAR AND FUNCTIONAL CORRELATION WITH VISUAL OUTCOMES.
СтатьяКлинический случайНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Azuma Keiko, Santo Daisuke, Sugiyama Satoshi, Aoki Nobuyori, Aoki Shuichiro, Kitamoto Kohdai, Terao Ryo, Inoue Tatsuya, Obata Ryo
Аннотация
PURPOSE: To investigate changes in melanin distribution and retinal sensitivity after a retinal pigment epithelium tear in neovascular age-related macular degeneration.
METHODS: Five cases of neovascular age-related macular degeneration with retinal pigment epithelium tears involving the fovea within 1 month of onset were examined. Using polarization-sensitive optical coherence tomography, entropy-a quantitative indicator of melanin distribution-was measured at baseline and 6 months at the level of Bruch membrane. Retinal sensitivity was assessed with a microperimeter, and entropy was averaged across 25 grids within a 6° radius. The relationship between changes in entropy and retinal sensitivity was analyzed.
RESULTS: Entropy significantly increased in the tear area (from 0.18 to 0.22, P< 0.0001), whereas it decreased in the nontear area. Retinal sensitivity also significantly increased in the tear area (from 12.7 to 16.3 dB, P <0.0001). Although entropy and retinal sensitivity were not directly correlated in each area, their changes were significantly correlated, regardless of area type. Changes in central grid entropy were associated with changes in logarithm of the minimum angle of resolution visual acuity.
CONCLUSION: Six months postretinal pigment epithelium tear, entropy and retinal sensitivity increased in tear areas; entropy changes were linked to retinal sensitivity and visual acuity, indicating functional adjustments after the tear.
METHODS: Five cases of neovascular age-related macular degeneration with retinal pigment epithelium tears involving the fovea within 1 month of onset were examined. Using polarization-sensitive optical coherence tomography, entropy-a quantitative indicator of melanin distribution-was measured at baseline and 6 months at the level of Bruch membrane. Retinal sensitivity was assessed with a microperimeter, and entropy was averaged across 25 grids within a 6° radius. The relationship between changes in entropy and retinal sensitivity was analyzed.
RESULTS: Entropy significantly increased in the tear area (from 0.18 to 0.22, P< 0.0001), whereas it decreased in the nontear area. Retinal sensitivity also significantly increased in the tear area (from 12.7 to 16.3 dB, P <0.0001). Although entropy and retinal sensitivity were not directly correlated in each area, their changes were significantly correlated, regardless of area type. Changes in central grid entropy were associated with changes in logarithm of the minimum angle of resolution visual acuity.
CONCLUSION: Six months postretinal pigment epithelium tear, entropy and retinal sensitivity increased in tear areas; entropy changes were linked to retinal sensitivity and visual acuity, indicating functional adjustments after the tear.