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Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023

Electrocardiographic findings in patients with arrhythmogenic cardiomyopathy and right bundle branch block ventricular tachycardia.

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Laredo Mikael, Tovia-Brodie Oholi, Milman Anat, Michowitz Yoav, Roudijk Rob W, Peretto Giovanni, Badenco Nicolas, Te Riele Anneline S J M, Sala Simone, Duthoit Guillaume, Arbelo Elena, Ninni Sandro, Gasperetti Alessio, van Tintelen J Peter, Paglino Gabriele, Waintraub Xavier, Andorin Antoine, Peichl Petr, Bosman Laurens P, Calo Leonardo, Giustetto Carla, Radinovic Andrea, Jorda Paloma, Casado-Arroyo Ruben, Zorio Esther, Bermúdez-Jiménez Francisco J, Behr Elijah R, Havranek Stepan, Tfelt-Hansen Jacob, Sacher Frederic, Hermida Jean-Sylvain, Nof Eyal, Casella Michela, Kautzner Josef, Lacroix Dominique, Brugada Josep, Duru Firat, Bella Paolo Della, Gandjbakhch Estelle, Hauer Richard, Belhassen Bernard

Аннотация

AIMS: Little is known about patients with right bundle branch block (RBBB)-ventricular tachycardia (VT) and arrhythmogenic cardiomyopathy (ACM). Our aims were: (i) to describe electrocardiogram (ECG) characteristics of sinus rhythm (SR) and VT; (ii) to correlate SR with RBBB-VT ECGs; and (iii) to compare VT ECGs with electro-anatomic mapping (EAM) data.

METHODS AND RESULTS: From the European Survey on ACM, 70 patients with spontaneous RBBB-VT were included. Putative left ventricular (LV) sites of origin (SOOs) were estimated with a VT-axis-derived methodology and confirmed by EAM data when available. Overall, 49 (70%) patients met definite Task Force Criteria. Low QRS voltage predominated in lateral leads (n = 37, 55%), but QRS fragmentation was more frequent in inferior leads (n = 15, 23%). T-wave inversion (TWI) was equally frequent in inferior (n = 28, 42%) and lateral (n = 27, 40%) leads. TWI in inferior leads was associated with reduced LV ejection fraction (LVEF; 46 ± 10 vs. 53 ± 8, P = 0.02). Regarding SOOs, the inferior wall harboured 31 (46%) SOOs, followed by the lateral wall (n = 17, 25%), the anterior wall (n = 15, 22%), and the septum (n = 4, 6%). EAM data were available for 16 patients and showed good concordance with the putative SOOs. In all patients with superior-axis RBBB-VT who underwent endo-epicardial VT activation mapping, VT originated from the LV.

CONCLUSIONS: In patients with ACM and RBBB-VT, RBBB-VTs originated mainly from the inferior and lateral LV walls. SR depolarization and repolarization abnormalities were frequent and associated with underlying variants.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты