Halothane-associated granulomatous hepatitis.

We present a case of halothane-associated-hepatitis in a 34-year-old woman. She received halothane anesthesia twice within a 6-day interval, 2 weeks prior to the onset of symptoms. Liver histology was nonspecific, and unusual in showing not only lobular hepatitis but also granulomatous changes. Since the clinical picture and the laboratory values were more and the liver histology less in keeping with the diagnosis, we emphasize that the former two parameters should play a vital role in establishing or discarding the diagnosis of halothane-induced hepatitis.