Journal of cutaneous medicine and surgery · 2012
Allergic contact dermatitis from dimethyl fumarate after contact with a Chinese sofa.
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Doumit Joseph, Gavigan Geneviève, Pratt Melanie
Аннотация
BACKGROUND: Dimethyl fumarate has been successfully used in the treatment of psoriasis in the past. Despite its clinical use, cutaneous contact with this molecule may cause contact dermatitis.
OBJECTIVE: We report a case in which skin exposure to a synthetic fabric sofa containing dimethyl fumarate made by a Chinese furniture manufacturer resulted in a severe, pruritic, papulovesicular, eczematous dermatitis to the sites of contact with the sofa.
METHODS: The patient was patch-tested with serial dilutions of dimethyl fumarate.
RESULTS: Patch testing results revealed strong positive reactions to dimethyl fumarate at different concentrations.
CONCLUSION: Dimethyl fumarate is a potent contact sensitizer and is commonly found in sachets inside furniture and footwear boxes.
OBJECTIVE: We report a case in which skin exposure to a synthetic fabric sofa containing dimethyl fumarate made by a Chinese furniture manufacturer resulted in a severe, pruritic, papulovesicular, eczematous dermatitis to the sites of contact with the sofa.
METHODS: The patient was patch-tested with serial dilutions of dimethyl fumarate.
RESULTS: Patch testing results revealed strong positive reactions to dimethyl fumarate at different concentrations.
CONCLUSION: Dimethyl fumarate is a potent contact sensitizer and is commonly found in sachets inside furniture and footwear boxes.