[The phenomenon of increasing of activity of aspartate transaminase in blood plasma ("macro-AST") in healthy persons].

The article considers the case of several years long increased level of activity of aspartate transaminase in blood plasma of clinically healthy persons from one family (belonging to Caucasioni type)--the father 35 years old and two biologic children, daughter 4 years old and son 3 years old. In all family members with hyper aspartate transaminasemia chronic diseases, alcohol and drugs consumption, regular use of certain medications and dietary supplements or impact of exogenous (ecologic) chemical factors producing persistent increase of activity of aspartate transaminase in blood plasma were totally excluded. On the basis of totality of anamnesis and results of clinical and laboratory examination the given condition was considered as "macro-AST" being a variant of biochemical phenomenon of "macro-enzymes".