Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2025
Characteristics of lower limb skeletal muscle activity during walking in patients with knee osteoarthritis and knee extensor weakness: Comprehensive assessment using positron emission tomography.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Sengoku Takuya, Oshima Takeshi, Takata Yasushi, Taki Junichi, Yanatori Yusuke, Sakurai Goro, Kinuya Seigo, Demura Satoru, Nakase Junsuke
Аннотация
PURPOSE: To compare the whole-body muscles glucose metabolism during walking among patients with knee osteoarthritis (KOA) with and without knee extensor weakness using 18F-fluorodeoxyglucose positron emission tomography (FDG-PET).
METHODS: Participants were divided into group A (n = 7) with good and group B (n = 15) with poor knee extensor strength, based on a weight-bearing ratio of 0.45 Nm/kg of the knee extensor strength required for walking adaptation. After treadmill walking task, FDG-PET computed tomography was performed, and standardised uptake values of glucose metabolism were calculated. Hip abductor and knee extensor strengths were measured using a handheld dynamometer. A comparison between the two groups and investigation into the correlation between glucose metabolism and muscle strength (hip abductor and knee extensor) were conducted.
RESULTS: No significant differences were observed in overall glucose metabolism; However, when adjusting for sex between the two groups, Group B exhibited higher glucose metabolism in the tibialis anterior muscle (P = 0.04). Furthermore, glucose metabolism in the rectus femoris muscle showed a negative correlation with muscle strength during isometric contractions for hip abductor and knee extensor.
CONCLUSION: Patients with KOA exhibiting reduced knee extensor strength have increased glucose metabolism in the tibialis anterior.
METHODS: Participants were divided into group A (n = 7) with good and group B (n = 15) with poor knee extensor strength, based on a weight-bearing ratio of 0.45 Nm/kg of the knee extensor strength required for walking adaptation. After treadmill walking task, FDG-PET computed tomography was performed, and standardised uptake values of glucose metabolism were calculated. Hip abductor and knee extensor strengths were measured using a handheld dynamometer. A comparison between the two groups and investigation into the correlation between glucose metabolism and muscle strength (hip abductor and knee extensor) were conducted.
RESULTS: No significant differences were observed in overall glucose metabolism; However, when adjusting for sex between the two groups, Group B exhibited higher glucose metabolism in the tibialis anterior muscle (P = 0.04). Furthermore, glucose metabolism in the rectus femoris muscle showed a negative correlation with muscle strength during isometric contractions for hip abductor and knee extensor.
CONCLUSION: Patients with KOA exhibiting reduced knee extensor strength have increased glucose metabolism in the tibialis anterior.