Scientific reports · 2022
Prevalence and characteristics of dry eye disease in Parkinson's disease: a systematic review and meta-analysis.
МетаанализСистематический обзорСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Nagino Ken, Sung Jaemyoung, Oyama Genko, Hayano Motoshi, Hattori Nobutaka, Okumura Yuichi, Fujio Kenta, Akasaki Yasutsugu, Huang Tianxiang, Midorikawa-Inomata Akie, Fujimoto Keiichi, Eguchi Atsuko, Hurramhon Shokirova, Miura Maria, Ohno Mizu, Hirosawa Kunihiko, Morooka Yuki, Murakami Akira, Kobayashi Hiroyuki, Inomata Takenori
Аннотация
We investigated and characterized the prevalence of dry eye disease (DED) in Parkinson's disease (PD). PubMed and EMBASE databases were searched for relevant studies between January 1, 1979 and March 10, 2022. Quality was assessed using the Joanna Briggs Institute Critical Appraisal Checklist. Study-specific estimates were combined using the DerSimonian-Laird random-effects model. Prevalence of subjective DED symptoms in patients with PD and mean differences in blink rate, corneal thickness, tear film breakup time, and tear secretion volume on Schirmer test I were compared to those in controls. Of 383 studies, 13 (1519 patients with PD) and 12 were included in qualitative and quantitative syntheses, respectively. Meta-analysis revealed a 61.1% prevalence of subjective DED symptoms in PD and that, compared with controls, patients with PD had significantly lower blink rate, thinner corneal thickness, shorter tear film breakup time, and lower tear secretion volumes on Schirmer test I, without and with anesthesia.