Infectious diseases (London, England) · 2019
Efficacy and safety of the switch of Triumeq® to generic (abacavir + lamivudine) + Tivicay®: data at 48 weeks.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Ошибки и ограничения
История · было → стало
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Pérez-Stachowski Javier, Tortajada Begoña, Del Arco Alfonso, Márquez Efrén, De la Torre Javier, Nieto Miriam, García de Lomas José María, Prada José Luis, García-Alegría Javier, Olalla Julián
Аннотация
Introduction: Generic drugs are helpful to enhance the efficiency of the sanitary system. A generic coformulation of abacavir (ABC) and lamivudine (3TC) is available since 2016 in Spain. A report of our experience with its use is exposed. Methods: Patients between February 2017 and June 2017 who were taking Triumeq® were switched to the generic ABC + 3TC plus DTG. Efficacy, safety, reasons for discontinuation and costs savings were evaluated at 48 weeks. Results: Switch was made in 93 patients, with a median age of 47 years and a mean time of 12.33 years with HIV infection. Six patients (6.5%) discontinued the new ART, being toxicity of the central nervous system the most frequent reason. The effective saving derived from the change after 1 year of treatment was 151.127 €. Conclusions: The change from Triumeq® to a generic regimen of ABC + 3TC and another pill of DTG seems to be safe and efficient at 48 weeks.