Threading the needle: Tips and tricks for challenging percutaneous abdominopelvic biopsies.

The growing use of biomarker testing for personalized oncologic care has increased the demand for complex and repeated percutaneous biopsies in abdominal and interventional radiology practices. Challenging biopsies can be daunting, requiring a careful assessment of feasibility, safety, and risk tolerance. Several strategies can help optimize the chances of achieving success. Such strategies include leveraging the advantages of the modality chosen for image guidance, ensuring patient comfort, and the use of special techniques, such as IV contrast, navigational tols, and biopsy needle modifications. This review outlines practical tips and tricks for radiologists performing challenging percutaneous biopsies.