European journal of radiology · 2025
Evaluation of multi-keV PureCalcium images from photon-counting CT for abdominal imaging: A comparison with true and conventional virtual non-contrast images.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Li Liming, Yao Yang, Nie Kehui, Yuan Mengchen, Fan Songmei, Gao Jianbo
Аннотация
PURPOSE: To determine which keV PureCa images can effectively substitute TNC images for abdominal imaging.
METHODS: A total of 50 consecutive patients who underwent thoracoabdominal scans on Photon-Counting CT from January to April 2025 were included. A true non-contrast (TNC), arterial (CTA) and venous (CTV) phase images were analyzed. Conventional virtual non-contrast (VNC) and 5 PureCa images were reconstructed from each contrast phase. Attenuation values and noise on 12 regions of interest were measured. Overall image quality, contrast removal and calcium preservation were analyzed using a 5-point scale. The paired t-tests and Friedman tests were applied to compare objective and subjective results.
RESULTS: 70 keV yielded the smallest HUerror in the majority of abdominal tissues during the arterial and venous phase. The overall trend demonstrated a plateau in noise reduction beyond 65 keV. Compared with VNC images, PureCa demonstrated significantly lower HUerror in key soft tissues: Liver: 2 (1-6) HU vs 5 (3-8) HU (P = 0.001), Muscle: 2 (1-4) HU vs 10 (7-14) HU (P < 0.001), subcutaneous adipose tissue: 2.5 (1-4) HU vs 39 (33-42) HU (P < 0.001). All patients had a subjective score of 3 or above. 65-70 keV PureCa images were rated significantly higher than 50-60 keV images, and comparable to VNC, but still inferior to TNC (P < 0.05).
CONCLUSIONS: PureCa images reconstructed at 70 keV on photon-counting CT systems provide accurate attenuation values and satisfactory image quality for abdominal tissues.
METHODS: A total of 50 consecutive patients who underwent thoracoabdominal scans on Photon-Counting CT from January to April 2025 were included. A true non-contrast (TNC), arterial (CTA) and venous (CTV) phase images were analyzed. Conventional virtual non-contrast (VNC) and 5 PureCa images were reconstructed from each contrast phase. Attenuation values and noise on 12 regions of interest were measured. Overall image quality, contrast removal and calcium preservation were analyzed using a 5-point scale. The paired t-tests and Friedman tests were applied to compare objective and subjective results.
RESULTS: 70 keV yielded the smallest HUerror in the majority of abdominal tissues during the arterial and venous phase. The overall trend demonstrated a plateau in noise reduction beyond 65 keV. Compared with VNC images, PureCa demonstrated significantly lower HUerror in key soft tissues: Liver: 2 (1-6) HU vs 5 (3-8) HU (P = 0.001), Muscle: 2 (1-4) HU vs 10 (7-14) HU (P < 0.001), subcutaneous adipose tissue: 2.5 (1-4) HU vs 39 (33-42) HU (P < 0.001). All patients had a subjective score of 3 or above. 65-70 keV PureCa images were rated significantly higher than 50-60 keV images, and comparable to VNC, but still inferior to TNC (P < 0.05).
CONCLUSIONS: PureCa images reconstructed at 70 keV on photon-counting CT systems provide accurate attenuation values and satisfactory image quality for abdominal tissues.